We've successfully fabricated a NWA structure.
HeaYeon Lee, Ph.D.
Founder and CEO
Mara Nanotech Korea, Inc., South Korea
Mara Nanotech New York, Inc., USA
Visiting Scholar, Bouve College of Health Sciences, Northeastern University, Boston, MA
Adjunct Professor, College of Human Ecology,
Chungnam Nat'l University, South Korea
160 Convent Ave., Steinman Hall, RM B20,
New York, NY 10031-9101, US
We have worked on digital nanobiomedical sensor system using electrochemical analysis and nanocosmeceudical with nanotechnology, nanobioscience, chemistry, material science and molecular engineering. Our company goal is to make nano-bio-diagnostic kits/system using nanowell array technology for health monitoring and nanocosmeceutical for skin health care. It is applicable in clinical medicine, skin healthcare, pharmacology, environmental industry.
Note that most hot issues in nanobiomedical technology, such as single biomolecule sensing devices, are still unsettled. I believe that a key solution to those issues could come from a nanoscale well array (NWA), which I have already proposed. Over the past 15 years, I have successfully fabricated a NWA structure using various nanofabrication methods and demonstrated that it can be used to fabricate a new nano-biosensor with ultra-high sensitivity and good reproducibility.
The geometry permits only one (or a few biomolecules) to enter and become attached to a nanosized substrate. When this array is applied to highly sensitive electrochemical DNA detection, a 150-orders-of-magnitude enhancement in sensitivity is obtained. This NWA system can be applied to numerous other integrated digital biomedical sensors. I have published several papers in important journals, and I have also been invited to several international conferences to give invited presentations. Most of these research results were generated from ideas I proposed myself.
HeaYeon Lee is a President/CEO in Mara Nanotech New York, Inc. and a Visiting Professor, Department of Pharmaceutical Sciences, Bouve College of Health Sciences, Northeastern University, Boston, MA.
She received her BS (1987) and MS degrees (1990) in Chemistry from Pukyong National University, South Korea and her Ph.D. degree (1995) in Chemistry from Osaka University, Japan. After finishing advanced degrees in nanofabrication and characterization technologies, she has been working on developing new nanobioelectronic devices and nanobiosensors. She was a Designated Professor at the Institute of Scientific and Industrial Research, Osaka University, and Research Associate Professor of Mechanical and Industrial Engineering at Northeastern University, Boston, USA. Her research work has been contributing to accelerating cutting-edge research in the emerging bio-nanoscience area.